Researchers in biosciences and life chemistry met "face-to-face" for the Biotechnocentre's thematic day on "Exposome and Epigenetics: how does the environment play with our genes?" ". Renowned speakers declined the different facets of the exposome: physical or chemical exposure or exposure to different pathogens, stress, diet, social inequalities... They also highlighted the impact of the exposome on the environment and on our health, which can have different consequences depending on gender, age, genetic heritage and on its regulation by reversible epigenetic modifications.