email : stephane.charpentier[remplacer_par_at]cnrs-orleans.fr
Phone : +33 2.38.25.55.96
Lecturer within the thematic group “Synthetic protein and Bioorthogonal Chemistry
- Métadonnées
Publications (Archives Hal)
Contact
isabelle.frapart@cnrs-orleans.fr 02.38.25.55.53
Disciplines
Mots-clefs
ANTIGENS Alpha-synuclein Antiretroviral therapy Apoptosis BAX Basal autophagy CELL-DEATH PROTEIN Caspase activation Cytogaligin Dual cellular localization Dual localization ELECTROPHORETIC TRANSFER ENDOGENOUS PEROXIDASE GALIG gene GENE HORSERADISH-PEROXIDASE IDENTIFICATION IMPORTIN INTRACELLULAR-LOCALIZATION MITOCHONDRIA
- GENE2
- MITOCHONDRIA2
- ANTIGENS1
- Alpha-synuclein1
- Antiretroviral therapy1
- Apoptosis1
- BAX1
- Basal autophagy1
- CELL-DEATH PROTEIN1
- Caspase activation1
- Cytogaligin1
- Dual cellular localization1
- Dual localization1
- ELECTROPHORETIC TRANSFER1
- ENDOGENOUS PEROXIDASE1
- GALIG gene1
- HORSERADISH-PEROXIDASE1
- IDENTIFICATION1
- IMPORTIN1
- INTRACELLULAR-LOCALIZATION1
- LOCALIZATION1
- Luciferase protein-fragment complementation assay1
- MOLECULAR-CLONING1
- Machine learning techniques for biomedical data1
- Mitogaligin1
- NITROCELLULOSE1
- P53 PROTEIN1
- POLYACRYLAMIDE GELS1
- PROTEINS1
- Programmed cell death1
- SEQUENCE1
- SMARF1
- TRANSLOCATION1
- Unconventional nuclear localization signal1
- VIRUS1
Auteurs
Charpentier Stéphane21 Legrand Alain13 Normand Thierry12 Mollet Lucile9 Brulé-Morabito Fabienne8 Dubois Martine6 Delfour Antoine3 Dubois M3 Gonzalez Patrick3 Haddad S El3 Nicolas Pierre3 Serrano A3 Robinet Pauline3 Carp D2 Delfour A2 Dubois M.2 El Haddad S.2 El Haddad Saïd2 Guery T2 Legac E2 Naim M2 Schoenwald M2 Serrano A.2 Serrano Amandine2 Robin Chloé2 Mollet L.2 Amiche Mohamed2 Sagan Sandrine2 Aurouet Axel1 Auzou P.1 Baron Daniel1 Boyer Guittaut M.1 Bralet Jean1 Caron Marc G.1 Costentin J.1 Duneau M.1 Duneau Mélanie1 Garnache-Ottou F1 Garnache-Ottou Francine1 Grandclement Camille1 Guittaut Michaël1 Hocqueloux L1 Jarvie Keith1 Le Caer Jean-Pierre1 Lecomte Jeanne-Marie1 Legac E.1 Legac Eric1 Moal F1 Moal F.1 Naim Mohamed1 Nicolas P1 Nicolas P.1 Normand T1 Ozsancak C1 Prazuck T1 Prazuck T.1 Prazuck Thierry1 Raimond J.1 Raimond Jacques1 Rohrlich Pierre Simon1 Rohrlich Ps1 Sagan S.1 Schwartz Jean-Charles1 Sennepin Alexis D.1 Severynse Diana1 Simon P1 Sureau Adelin1 Tiberi Mario1 Valery A1 Vouille Véronique1 Brule Fabienne1 Normand T.1 Legrand A.1 Charpentier S.1 Charpentier Stephane1 Mollet Lucile M.1 Gonzalez P.1 Sarre Cedric1 Nicolas Pierre1 Deconinck Eric1 Hocqueloux Laurent1 Sagan S1 Gros Claude1 Moal Fréderic1 Mester Jan1 Mossiat Claude1
Revues
- Biochemical and Biophysical Research Communications5
- Journal of Biological Chemistry3
- European Journal of Pharmacology2
- Analytical Biochemistry1
- Biopolymers1
- AIDS. Official journal of the international AIDS Society1
- Methods and findings in experimental and clinical pharmacology1
- Molecular Immunology1
- Peptides1
- Biochemistry1
Institutions
- Université d'Orléans14
- Université de Tours14
- Institut National de la Santé et de la Recherche Médicale14
- Institut de Chimie - CNRS Chimie14
- Université Paris Diderot - Paris 78
- Centre Hospitalier Régional d'Orléans2
- Université de Bordeaux1
- Centre Hospitalier Régional Universitaire de Besançon1
- Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris1
- Institut National des Sciences Appliquées - Centre Val de Loire1
- Société GéoHyd1
- Institut Polytechnique de Bordeaux1
- Etablissement français du sang [Bourgogne-Franche-Comté]1
- Université Grenoble Alpes [2016-2019]1
- Université de Franche-Comté1
- Université Bordeaux Segalen - Bordeaux 21
- Université Sciences et Technologies - Bordeaux 11
- Université Pierre et Marie Curie - Paris 61
- Duke University [Durham]1
Laboratoires
- Centre de biophysique moléculaire14
- Institut Jacques Monod8
- Service d'hématologie1
- Neurobiologie et diversité cellulaire1
- Interactions hôte-greffon-tumeur, ingénierie cellulaire et génique - UFC (UMR INSERM 1098)1
- Société GéoHyd1
- Laboratoire d'Informatique Fondamentale d'Orléans1
- Institut Pierre Louis d'Epidémiologie et de Santé Publique1
- Institut de Mathématiques de Bordeaux1
- Laboratoire Paul Painlevé - UMR 85241
Départements
Équipes de recherche
23 documents
Article dans une revue18 documents
- Saïd El Haddad, Amandine Serrano, Thierry Normand, Chloé Robin, Martine Dubois, et al.. Interaction of Alpha-synuclein with Cytogaligin, a protein encoded by the proapoptotic gene GALIG. Biochemical and Biophysical Research Communications, 2018, 495 (1), pp.787-792. ⟨10.1016/j.bbrc.2017.11.078⟩. ⟨hal-01966108⟩
- Amandine Serrano, Saïd El Haddad, Fréderic Moal, Thierry Prazuck, Eric Legac, et al.. Dysregulation of apoptosis and autophagy gene expression in peripheral blood mononuclear cells of efficiently treated HIV-infected patients. AIDS. Official journal of the international AIDS Society, 2018, 32 (12), pp.1579 - 1587. ⟨10.1097/QAD.0000000000001851⟩. ⟨hal-01936094⟩
- Lucile Mollet, Pauline Robinet, Martine Dubois, Axel Aurouet, Thierry Normand, et al.. Opposing Mcl-1, the GALIG proapoptotic gene is upregulated as neutrophils die and underexpressed in Acute Myeloid Leukemia cells.. Molecular Immunology, 2013, 56 (1-2), pp.123-8. ⟨10.1016/j.molimm.2013.04.012⟩. ⟨hal-00840170⟩
- Pauline Robinet, Lucile Mollet, Patrick Gonzalez, Thierry Normand, Stephane Charpentier, et al.. The mitogaligin protein is addressed to the nucleus via a non-classical localization signal. Biochemical and Biophysical Research Communications, 2010, 392 (1), pp.53-57. ⟨10.1016/j.bbrc.2009.12.162⟩. ⟨hal-00529397⟩
- Alexis D. Sennepin, Stéphane Charpentier, Thierry Normand, Cedric Sarre, Alain Legrand, et al.. Multiple reprobing of Western blots after inactivation of peroxidase activity by its substrate, hydrogen peroxide. Analytical Biochemistry, 2009, 393 (1), pp.129-131. ⟨10.1016/j.ab.2009.06.004⟩. ⟨hal-00525339⟩
- Patrick Gonzalez, Pauline Robinet, Stéphane Charpentier, Lucile Mollet, Thierry Normand, et al.. Apoptotic activity of a nuclear form of mitogaligin, a cell death protein. Biochemical and Biophysical Research Communications, 2009, 378 (4), pp.816-820. ⟨10.1016/j.bbrc.2008.11.133⟩. ⟨hal-00522444⟩
- Patrick Gonzalez, Mélanie Duneau, Stéphane Charpentier, Thierry Normand, Lucile Mollet, et al.. Destabilization of Membranes Containing Cardiolipin or Its Precursors by Peptides Derived from Mitogaligin, a Cell Death Protein. Biochemistry, 2007, 46 (25), pp.7374-7382. ⟨10.1021/bi700213p⟩. ⟨hal-00159568⟩
- M. Duneau, M. Boyer Guittaut, P. Gonzalez, S. Charpentier, T. Normand, et al.. Galig, a novel cell death gene that encodes a mitochondrial protein promoting cytochrome c release. Experimental Cell Research, 2005, 302, pp.194-205. ⟨hal-00088588⟩
- Michaël Guittaut, Stéphane Charpentier, Thierry Normand, Martine Dubois, Jacques Raimond, et al.. Identification of an Internal Gene to the Human Galectin-3 Gene with Two Different Overlapping Reading Frames That Do Not Encode Galectin-3. Journal of Biological Chemistry, 2001, 276 (4), pp.2652-2657. ⟨10.1074/jbc.m002523200⟩. ⟨hal-02137994⟩
- Stéphane Charpentier, Mohamed Amiche, Jan Mester, Véronique Vouille, Jean-Pierre Le Caer, et al.. Structure, Synthesis, and Molecular Cloning of Dermaseptins B, a Family of Skin Peptide Antibiotics. Journal of Biological Chemistry, 1998, 273 (24), pp.14690-14697. ⟨10.1074/jbc.273.24.14690⟩. ⟨hal-02160836⟩
- Stéphane Charpentier, Keith Jarvie, Diana Severynse, Marc G. Caron, Mario Tiberi. Silencing of the Constitutive Activity of the Dopamine D1B Receptor. Journal of Biological Chemistry, 1996, 271 (45), pp.28071-28076. ⟨10.1074/jbc.271.45.28071⟩. ⟨hal-02160838⟩
- Stéphane Charpentier, S. Sagan, M Naim, A Delfour, P. Nicolas. Mechanism of delta-opioid receptor selection by the address domain of dermenkephalin.. European Journal of Pharmacology, 1994, 266 (2), pp.175-80. ⟨10.1016/0922-4106(94)90107-4⟩. ⟨hal-02160840⟩
- Mohamed Naim, Stéphane Charpentier, Pierre Nicolas, Daniel Baron. Quantitative two-dimensional nmr study of dermenkephalin, a highly potent and selective ?-opioid peptide. Biopolymers, 1993, 33 (12), pp.1889-1900. ⟨10.1002/bip.360331214⟩. ⟨hal-02160842⟩
- Sandrine Sagan, Stéphane Charpentier, Antoine Delfour, Mohamed Amiche, Pierre Nicolas. The aspartic acid in deltorphin I and dermenkephalin promotes targeting to δ-opioid receptor independently of receptor binding. Biochemical and Biophysical Research Communications, 1992, 187 (3), pp.1203-1210. ⟨10.1016/0006-291X(92)90431-J⟩. ⟨hal-02171853⟩
- S Sagan, Stéphane Charpentier, M Naim, A Delfour, P Nicolas. Opioid peptides from amphibian skin: contribution of the amino acids of the "address" domain to the -selectivity of dermenkephalin. Peptides, 1992, pp.645-646. ⟨hal-02171902⟩
- Stéphane Charpentier, Sandrine Sagan, Antoine Delfour, Pierre Nicolas. Dermenkephalin and deltorphin I reveal similarities within ligand-binding domains of μ- and δ-opioid receptors and an additional address subsite on the δ-receptor. Biochemical and Biophysical Research Communications, 1991, 179 (3), pp.1161-1168. ⟨10.1016/0006-291x(91)91693-7⟩. ⟨hal-02171883⟩
- P Simon, Stéphane Charpentier, J. Costentin. An automated method for the assessment of spontaneous and stereotyped climbing behavior in mice. Effects of the selective D1- and D2-dopamine receptor agonists SKF-38393 and RU-24926 and their association.. Methods and findings in experimental and clinical pharmacology, 1991, 13 (2), pp.99-104. ⟨hal-02171886⟩
- Jean Bralet, Claude Mossiat, Jeanne-Marie Lecomte, Stéphane Charpentier, Claude Gros, et al.. Diuretic and natriuretic responses in rats treated with enkephalinase inhibitors. European Journal of Pharmacology, 1990, 179 (1-2), pp.57-64. ⟨10.1016/0014-2999(90)90401-q⟩. ⟨hal-02171891⟩
Communication dans un congrès5 documents
- S. El Haddad, A. Serrano, Thierry Normand, Fabienne Brulé-Morabito, L. Mollet, et al.. Cytogaligin, an additional link between Parkinson’s disease and autophagy pathways?. 7e Congrès du CFATG, Nov 2017, Paris, France. ⟨hal-02934905⟩
- A. Serrano, Thierry Normand, S. El Haddad, M. Dubois, Stéphane Charpentier, et al.. During efficient Anti-RetroViral (ARV) therapy, the expression of GALIG and its interacting partners involved in macroautophagy are deregulated. 6es Journées Scientifiques du CFATG, Oct 2016, Bordeaux, France. ⟨hal-02934903⟩
- S El Haddad, A Serrano, C Ozsancak, P. Auzou, F Moal, et al.. Genes de l’autophagie : marqueurs sanguins potentiels de la maladie de Parkinson. Journées de Neurologie de Langue Française, Apr 2016, Nantes, France. ⟨hal-03661930⟩
- A Serrano, S El Haddad, T Normand, M Dubois, T Guery, et al.. Cytogaligin, one of the proteins produced by the proapoptotic GALIG gene, interacts with autophagy and proteasome molecules. 7th Proteasome Autophagy Workshop, Apr 2016, Clermont-Ferrand, France. ⟨hal-03661923⟩
- A Serrano, T Guery, S El Haddad, M Dubois, M Schoenwald, et al.. GALIG, gène inducteur de la mort cellulaire, s’exprime au cours de la différenciation myéloïde. 10es Journées du Cancéropole Grand Ouest, Jun 2016, Les Sables d'Olonne, France. ⟨hal-03661932⟩