email : francoise.paquet[remplacer_par_at]cnrs-orleans.fr
Phone : +33 2.38.25.76.92
Researcher within the thematic group “NMR of biomolecules“
- Métadonnées
Publications (Archives Hal)
Contact
isabelle.frapart@cnrs-orleans.fr 02.38.25.55.53
Disciplines
- Sciences du Vivant [q-bio]31
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire8
- Chimie6
- Chimie/Chimie analytique5
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Biologie structurale [q-bio.BM]5
- Sciences du Vivant [q-bio]/Toxicologie2
- Sciences du Vivant [q-bio]/Biologie animale/Zoologie des invertébrés1
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Génomique, Transcriptomique et Protéomique [q-bio.GN]1
- Sciences du Vivant [q-bio]/Biologie cellulaire/Interactions cellulaires [q-bio.CB]1
- Sciences du Vivant [q-bio]/Biologie végétale1
- Sciences du Vivant [q-bio]/Génétique1
- Sciences du Vivant [q-bio]/Immunologie/Vaccinologie1
- Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Maladies émergentes1
- Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Maladies infectieuses1
Mots-clefs
3D structure ACTIVATION APOPTOSIS Ant venoms Ant venoms neurotoxins Tetramorium bicarinatum potassium channel helix peptide Aphid BCR Arabidopsis halleri Archaea Arm BINDING Benzylidene Bioinsecticidal peptide Bulges CHROMOSOMAL-PROTEIN CIS CISPLATIN DNA DNA MINICIRCLES DNA bending DNA-binding protein
- BINDING2
- 3D structure1
- ACTIVATION1
- APOPTOSIS1
- Ant venoms1
- Ant venoms neurotoxins Tetramorium bicarinatum potassium channel helix peptide1
- Aphid BCR1
- Arabidopsis halleri1
- Archaea1
- Arm1
- Benzylidene1
- Bioinsecticidal peptide1
- Bulges1
- CHROMOSOMAL-PROTEIN1
- CIS1
- CISPLATIN1
- DNA1
- DNA MINICIRCLES1
- DNA bending1
- DNA-binding protein1
- DNA/protein complex1
- Defensin peptide1
- Dimeric peptide1
- FORM1
- HISTONE1
- HU PROTEIN1
- Helix peptide1
- Human1
- L-fucose1
- MACROMOLECULES1
- MAGNETIC-RESONANCE RELAXATION1
- MC11
- MODEL-FREE APPROACH1
- Minor groove1
- Molecular complex1
- Molecular dynamics MD simulation1
- Molecular interaction1
- NMR1
- NMR relaxation1
- NMR spectrometry1
- NMR structure1
- Neurotoxins1
- Nucleoprotein1
- PLATINUM ANTITUMOR COMPLEXES1
- Potassium channel1
- Protooncogene1
- RESIDUAL DIPOLAR COUPLINGS1
- Secapins1
- Solid-phase synthesis1
- Symbiosis1
- Telomere1
- Tetramorium bicarinatum1
- Thiophenyl1
- Toxin precursor1
- Transcription factor1
- Trichloroacetimidate1
- Voltage-gated sodium channel Na V peptide1
- Zinc tolerance1
Auteurs
Paquet Françoise46 Loth Karine12 Delmas A.F.9 Jouvensal Laurence7 Castaing Bertrand7 Lancelot G.6 Landon Celine6 Largillière Justine6 Lancelot Gérard5 Touchard Axel5 Loth K.5 Landon Céline5 Chen Guang-Wu4 Climent Yanet4 Fernandez Sonsire4 Garcia-Rivera Dagmar4 Garrido Raine4 Hernandez Tays4 Leprince Jérôme4 Coste Franck4 Aucagne V.4 Meudal H.4 Landon C.4 Chiodo Fabrizio4 Culard Françoise4 Beau Jean-Marie3 Bencomo Vicente Verez3 Culard Françoise3 Sanchez Ramirez Belinda3 Santana-Mederos Darielys3 Sinaÿ Pierre3 Treilhou Michel3 Valdes-Balbin Yury3 Billet Arnaud3 Bonnafé Elsa3 Barassé Valentine3 Rivera Daniel3 Boggiano Tammy2 Bonnafé Elsa2 Cardoso Felix2 Castellanos-Serra Lila2 Enriquez Juliet2 Fang Cheng2 Gaudin G.2 Genest Daniel2 Gonzalez Humberto2 Labrada Regalado Claudia2 Landys Mario2 Leon Kalet2 Maurizot Jean-Claude2 Ojito Eduardo2 Petit Jean-Michel2 Ramirez Ubel2 Rodríguez Laura2 Rojas Gertrudis2 Lefranc Benjamin2 Aucagne Vincent2 Paquet F.2 Delmas Agnès F2 Treilhou Michel2 Téné Nathan2 Ascoët Steven2 Calevro Federica2 Ribeiro Lopes Mélanie2 Ramos Yassel2 Garrido Arteaga Raine2 Acosta Claudia1 Arnoult C.1 Ascoët Steven1 Asseline Ulysse1 Aumer Thomas1 Balbin Yury Valdes1 Balbín Yury Valdés1 Barassé Valentine1 Beau J-M1 Bergado Gretchen1 Bermudez Ernesto1 Bilbille Y.1 Billet Arnaud1 Boy Guillaume1 Brulé Fabienne1 Cabrera Infante Yanelys1 Carmenate Tania1 Casadesus Ana Victoria1 Catelani G.1 Catelani Giorgio1 Chanteloup L1 Culard Francoise1 Delalande Olivier1 Diaz Marianniz1 Espinosa Luis1 Espinosa Luis Ariel1 Farinas Mildrey1 Fernandez Briandy1 Fernández Sonsire1 Gaget Karen1 Gaudin F1 Gonzalez Luis Javier1 Gonzalez Nibaldo1 Hernandez Tamara1
Revues
Année de production
Institutions
- Université d'Orléans48
- Université de Tours42
- Institut National de la Santé et de la Recherche Médicale42
- Institut de Chimie - CNRS Chimie42
- Finlay Institute of Vaccines6
- Institut national universitaire Champollion [Albi]4
- Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement4
- Centre de Coopération Internationale en Recherche Agronomique pour le Développement3
- AgroParisTech3
- Université de Rouen Normandie3
- Université de Guyane3
- Institut National des Sciences Appliquées de Lyon2
- University of Havana (Universidad de la Habana)2
- Université de Montpellier2
- Sichuan University [Chengdu]2
- Center of Molecular Immunology, Havana2
- Vrije Universiteit Amsterdam [Amsterdam]2
- Université de Rennes1
- Center of Molecular Immunology1
- Université Claude Bernard Lyon 11
- Université de Douala1
- Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]1
- Structure Fédérative de Recherche en Biologie et Santé de Rennes1
- Institut national d’études supérieures agronomiques de Montpellier1
- Center for Genetic Engineering and Biotechnology [Cuba]1
- Institut National de la Recherche Agronomique1
- Centre international d'études supérieures en sciences agronomiques1
Laboratoires
- Centre de biophysique moléculaire42
- Laboratoire de biochimie structurale (1978-1990)5
- Biochimie et Toxicologie des Substances Bioactives4
- Ecologie des forêts de Guyane3
- Biologie Fonctionnelle, Insectes et Interactions2
- High-tech Research Infrastructures for Life Sciences2
- Unité de Mathématiques et Informatique Appliquées de Toulouse1
- Différenciation et communication neuronale et neuroendocrine1
- Neuroendocrine, Endocrine and Germinal Differentiation Communication1
- Institut de Génétique et Développement de Rennes1
Départements
Équipes de recherche
48 documents
Article dans une revue31 documents
- Valentine Barassé, Laurence Jouvensal, Guillaume Boy, Arnaud Billet, Steven Ascoët, et al.. Discovery of an Insect Neuroactive Helix Ring Peptide from Ant Venom. Toxins, 2023, 15 (10), pp.600. ⟨10.3390/toxins15100600⟩. ⟨hal-04390519⟩
- Steven Ascoët, Axel Touchard, Nathan Téné, Benjamin Lefranc, Jérôme Leprince, et al.. The mechanism underlying toxicity of a venom peptide against insects reveals how ants are master at disrupting membranes. iScience, 2023, 26 (3), pp.106157. ⟨10.1016/j.isci.2023.106157⟩. ⟨hal-04071274⟩
- Valentine Barassé, Nathan Téné, Christophe Klopp, Françoise Paquet, Niklas Tysklind, et al.. Venomics survey of six myrmicine ants provides insights into the molecular and structural diversity of their peptide toxins. Insect Biochemistry and Molecular Biology, 2022, 151, pp. 103876. ⟨10.1016/j.ibmb.2022.103876⟩. ⟨hal-04446316⟩
- Karine Loth, Nicolas Parisot, Françoise Paquet, Hugo Terrasson, Catherine Sivignon, et al.. Aphid BCR4 Structure and Activity Uncover a New Defensin Peptide Superfamily. International Journal of Molecular Sciences, 2022, 23 (20), pp.12480. ⟨10.3390/ijms232012480⟩. ⟨hal-03862651⟩
- Darielys Santana, Rocmira Perez Nicado, Yanet Climent, Laura Marta Marta Rodríguez Noda, Belinda Sánchez Ramírez, et al.. A COVID-19 vaccine candidate composed of SARS-CoV-2 RBD dimer and Neisseria meningitidis outer membrane vesicles. RSC Chemical Biology, 2022, 3 (2), pp.242-249. ⟨10.1039/D1CB00200G⟩. ⟨hal-03519898v2⟩
- Yury Valdes-Balbin, Darielys Santana-Mederos, Françoise Paquet, Sonsire Fernandez, Yanet Climent, et al.. Molecular Aspects Concerning the Use of the SARS-CoV-2 Receptor Binding Domain as a Target for Preventive Vaccines. ACS Central Science, 2021, 7, pp.757 - 767. ⟨10.1021/acscentsci.1c00216⟩. ⟨hal-04446345⟩
- Yury Valdes-Balbin, Darielys Santana-Mederos, Lauren Quintero, Sonsire Fernández, Laura Rodriguez, et al.. SARS-CoV-2 RBD-Tetanus Toxoid Conjugate Vaccine Induces a Strong Neutralizing Immunity in Preclinical Studies. ACS Chemical Biology, 2021, 16 (7), pp.1223-1233. ⟨10.1021/acschembio.1c00272⟩. ⟨hal-03443835⟩
- Yury Valdes-Balbin, Darielys Santana-Mederos, Françoise Paquet, Sonsire Fernandez, Yanet Climent, et al.. Molecular Aspects Concerning the Use of the SARS-CoV-2 Receptor Binding Domain as a Target for Preventive Vaccines. ACS Central Science, 2021, 7 (5), pp.757-767. ⟨10.1021/acscentsci.1c00216⟩. ⟨hal-03327027⟩
- Blanca I Tolón Murguía, Yuleidys de Las Mercedes Iglesias Morales, Miriam Mesa Hernández, Yaneisy Yu Pérez, Claudia Labrada Regalado, et al.. An efficient synthetic route to O-(2-O-benzyl-3,4-di-O-acetyl-α/β-l-fucopyranosyl)-trichloroacetimidate. Carbohydrate Research, 2020, 499, ⟨10.1016/j.carres.2020.108221⟩. ⟨hal-03432512⟩
- Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Céline Landon, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a sharp V-turn DNA structure. Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-50211-2⟩. ⟨hal-02306224⟩
- Karine Loth, Céline Landon, Françoise Paquet. Chemical shifts assignments of the archaeal MC1 protein and a strongly bent 15 base pairs DNA duplex in complex. Biomolecular NMR Assignments, 2015, 9 (1), pp.215-217. ⟨10.1007/s12104-014-9577-8⟩. ⟨hal-01171478⟩
- Fanny Meindre, Dominique Lelièvre, Karine Loth, Oriane Mith, Vincent Aucagne, et al.. The nuclear magnetic resonance solution structure of the synthetic AhPDF1.1b plant defensin evidences the structural feature within the γ-motif. Biochemistry, 2014, 53 (49), pp.7745-54. ⟨10.1021/bi501285k⟩. ⟨hal-01118914⟩
- Françoise Paquet, Olivier Delalande, Stephane Goffinont, Françoise Culard, Karine Loth, et al.. Model of a DNA-protein complex of the architectural monomeric protein MC1 from Euryarchaea. PLoS ONE, 2014, 9 (2), pp.e88809. ⟨10.1371/journal.pone.0088809⟩. ⟨hal-01063974⟩
- Violette Senille, Dominique Lelievre, Françoise Paquet, Norbert Garnier, Ned Lamb, et al.. The addressing fragment of mitogaligin: first insights into functional and structural properties.. ChemBioChem, 2013, 14 (6), pp.711-20. ⟨10.1002/cbic.201200715⟩. ⟨hal-00817503⟩
- Françoise Paquet, Karine Loth, Hervé Meudal, Francoise Culard, Daniel Genest, et al.. Refined solution structure and backbone dynamics of the archaeal MC1 protein. FEBS Journal, 2010, 277 (24), pp.5133-5145. ⟨10.1111/j.1742-4658.2010.07927.x⟩. ⟨hal-00602469⟩
- Y. Bilbille, F. Paquet, H. Meudal, M.J. Giraud-Panis, G. Lancelot. NMR studies of telomeric nucleoprotein complexes involving the Myb-like domain of the human telomeric protein TRF2. Comptes Rendus. Chimie, 2006, 9 (3-4), pp.452-458. ⟨10.1016/j.crci.2005.06.019⟩. ⟨hal-00088835⟩
- F. Kieken, F. Paquet, Fabienne Brulé, J. Paoletti, G. Lancelot. A new NMR solution structure of the SL1 HIV-1Lai loop-loop dimmer. Nucleic Acids Research, 2006, 34, pp.343-352. ⟨10.1093/nar/gkj427⟩. ⟨hal-00088868⟩
- Françoise Paquet, Françoise Culard, Florent Barbault, Jean-Claude Maurizot, Gérard Lancelot. NMR Solution Structure of the Archaebacterial Chromosomal Protein MC1 Reveals a New Protein Fold ‡. Biochemistry, 2004, 43 (47), pp.14971-14978. ⟨10.1021/bi048382z⟩. ⟨hal-02121481⟩
- Françoise Paquet, Jean-Claude Maurizot, Gérard Lancelot. Changes inlac Operator dynamics upon selective interaction withlac Repressor as revealed by heteronuclear relaxation rate measurements. Magnetic Resonance in Chemistry, 2000, 38 (11), pp.946-950. 3.0.CO;2-Q">⟨10.1002/1097-458X(200011)38:11<946::AID-MRC763>3.0.CO;2-Q⟩. ⟨hal-02121469⟩
- Françoise Paquet, Marc Boudvillain, Gérard Lancelot, Marc Leng. NMR solution structure of a DNA dodecamer containing a transplatin interstrand GN7-CN3 cross-link. Nucleic Acids Research, 1999, 27 (21), pp.4261-4268. ⟨10.1093/nar/27.21.4261⟩. ⟨hal-02075311⟩
- F Gaudin, Françoise Paquet, N.T Thuong, Daniel Genest, G. Lancelot. Selectively 13-C enriched DNA : Evidence of fast and slow internal motions. Journal of Biomolecular Structure and Dynamics, 1997, 26 (1), pp.45. ⟨hal-02132728⟩
- Françoise Paquet, C. Perez, M. Leng, G. Lancelot, J-M Malinge. NMR Solution Structure of a DNA Decamer Containing an Interstrand Cross-link of the Antitumor Drug cis -diamminedichloroplatinum(II). Journal of Biomolecular Structure and Dynamics, 1997, 14 (1), pp.67-77. ⟨10.1080/07391102.1996.10508930⟩. ⟨hal-02121444⟩
- Françoise Paquet, G. Gaudin, G. Lancelot. Selectively 13C-enriched DNA: evidence from 13C1' relaxation rate measurements of an internal dynamics sequence effect in the lac operator.. Journal of Biomolecular NMR, 1996, 8 (3), pp.252-60. ⟨hal-02121439⟩
- G. Gaudin, Françoise Paquet, L Chanteloup, J-M Beau, T. Nguyen, et al.. Selectively 13C-enriched DNA: dynamics of the C1'-H1' vector in d(CGCAAATTTGCG)2.. Journal of Biomolecular NMR, 1995, 5 (1), pp.49-58. ⟨hal-02121433⟩
- Jean-Michel Petit, Françoise Paquet, Jean-Marie Beau. Syntheses of β-2-deoxy-D-glycosides assisted by glycosidases. Tetrahedron Letters, 1991, 32 (43), pp.6125-6128. ⟨10.1016/0040-4039(91)80769-3⟩. ⟨hal-02121425⟩
- Jean-Michel Petit, Françoise Paquet, Jean-Marie Beau. Syntheses of β-2-deoxy-D-glycosides assisted by glycosidases. Tetrahedron Letters, 1991, 32 (43), pp.6125-6128. ⟨10.1016/0040-4039(91)80769-3⟩. ⟨hal-03519976⟩
- Jean-Marc Lancelin, Françoise Paquet, Jean-Marie Beau. Stereochemical studies on the polyene macrolide nystatin A1: the hydroxyl groups in the C-1—C-10 fragment are all-syn. Tetrahedron Letters, 1988, 29 (23), pp.2827-2830. ⟨10.1016/0040-4039(88)85222-5⟩. ⟨hal-02121419⟩
- G. Catelani, A. Marra, Françoise Paquet, P Sinaÿ. Chemical synthesis of the desialylated human Cad-anti-genic determinant.. Carbohydrate Research, 1986, 155, pp.131-40. ⟨hal-02121411⟩
- Giorgio Catelani, Alberto Marra, Françoise Paquet, Pierre Sinaÿ. Synthesis of trisaccharide derivatives with the sequence of the desialylated Cad blood groop determinant.. Gazetta Chimica Italiana, 1985, 115, pp.565-567. ⟨hal-02132694⟩
- Françoise Paquet, Pierre Sinaÿ. Intramolecular oximercuration-demercuration reaction: a new stereocontrolled approach to sialic acid containing disaccharides. Tetrahedron Letters, 1984, 25 (29), pp.3071-3074. ⟨10.1016/0040-4039(84)80010-6⟩. ⟨hal-02121392⟩
- Françoise Paquet, Pierre Sinaÿ. A new stereocontrolled approach to KDO containing disaccharides. Journal of the American Chemical Society, 1984, 106 (26), pp.8313-8315. ⟨10.1021/ja00338a062⟩. ⟨hal-02121396⟩
Communication dans un congrès3 documents
- Françoise Paquet, Sonsire Fernandez, Dagmar Garcia Rivera, Yury Valdes Balbin, Vicente Verez Bencomo. RSV F protein as target for vaccines. VACCIPHARMA 2023, Jun 2023, Varadero, Cuba. ⟨hal-04406393⟩
- Françoise Paquet, Darielys Santana Mederos, Raine Garrido Arteaga, Daniel García Rivera, Yury Valdés Balbín, et al.. Structural biology for vaccine development : the example of SOBERANA vaccines. BIOHABANA 2022, Apr 2022, La Havane (Cuba), Cuba. ⟨hal-04406363⟩
- Françoise Paquet. Séminaire invité : Unraveling the interaction between the capsular polysaccharide of Streptococcus pneumoniae type 6B and the anti-6B Monoclonal Antibody using an NMR approach. Finlay Institute of Vaccines, Sep 2018, La Havane, Cuba. ⟨hal-03604330⟩
Poster13 documents
- Laurence Jouvensal, Karine Loth, Axel Touchard, Arnaud Billet, Michel Treilhou, et al.. Diversity of host defense peptides in the venom of the ant T. bicarinatum. MuFoPAM 2023, Oct 2023, Lille, France. ⟨hal-04406429⟩
- Françoise Paquet, Thomas Aumer, Ons Kharrat, Thomas Knoblock, Philippe Bulet, et al.. First insight into interactions of an antifungal insect defensin with mimetic membranes containing glycosylceramides, by NMR spectroscopy.. 8es journées annuelles du GDR MuFoPAM, Oct 2021, Marseille, France. ⟨hal-03519915⟩
- Steven Ascoët, Nathan Téné, Axel Touchard, Jérôme Leprince, Françoise Paquet, et al.. Comparative investigation of the mechanisms of two cytotoxic venom peptides from the ant Tetramorium bicarinatum.. e-RT27 – 27th Meeting of the French Society of Toxinology, Dec 2021, virtual, France. ⟨hal-03519944⟩
- Herve Meudal, Françoise Paquet, Laurence Jouvensal, V. Aucagne, A.F. Delmas, et al.. Chemical synthesis and natural abundance NMR: an efficient tandem to unravel 3D structures of unlabeled disulfide rich peptides. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02919180⟩
- Françoise Paquet, K. Loth, C. Arnoult, V. Aucagne, A.F. Delmas. Spermaurin, a scorpion venom disulfide-rich miniprotein that improves sperm motility and fertilization in mammals.. 21e réunion du Groupe Français des Peptides et des Protéines (GFPP21), May 2019, Amboise, France. ⟨hal-02893462⟩
- Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a V-turn structure.. 28th ICMRBS - International Council on Magnetic Resonance in Biological Systems, Aug 2018, Dublin, Ireland. ⟨hal-02362584⟩
- H. Meudal, Laurence Jouvensal, K. Loth, Françoise Paquet, V. Aucagne, et al.. Chemical synthesis and natural abundance NMR: An efficient tandem to unravel 3D structures of Disulfide Rich Miniproteins. 35th European Peptide Symposium, Aug 2018, Dublin, Ireland. ⟨hal-02920483⟩
- Karine Loth, Justine Largillière, Franck Coste, Françoise Culard, Celine Landon, et al.. New protein-DNA complexes in archaea: a small monomeric protein induces a sharp V-turn DNA structure.. EuroMar 2018, Jul 2018, Nantes, France. ⟨hal-02362581⟩
- Karine Loth, Françoise Culard, Justine Largillière, Celine Landon, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a monomeric protein induces a U-turn structure.. 5e séminaire scientifique du LIA MiR-TANGo, May 2018, Orléans, France. ⟨hal-02362804⟩
- Françoise Paquet, H. Meudal, Laurence Jouvensal, K. Loth, V. Aucagne, et al.. Synthèse chimique et RMN en abondance naturelle : un tandem efficace pour résoudre les structures 3D de peptides/protéines riches en ponts disulfure. 5es journées annuelles du GDR MuFoPAM, Oct 2018, Paris, France. ⟨hal-02920025⟩
- Karine Loth, Françoise Culard, Justine Largillière, Celine Landon, Bertrand Castaing, et al.. The MC1-DNA complex solution structure reveals that a monomeric protein can induce a U-turn in archaea.. NMR: a tool for biology XTh, Jan 2017, Paris, France. ⟨hal-02361613⟩
- Karine Loth, Justine Largillière, Franck Coste, A.F. Delmas, Bertrand Castaing, et al.. New protein-DNA complexes in archaea: a monomeric protein induces a U-turn structure.. Le Studium Confenrence: Structural biology and biophysics of RNA-protein complexes, Nov 2017, Orléans, France. ⟨hal-02362576⟩
- H. Meudal, Marylène Bertrand, Laurence Jouvensal, A.F. Delmas, Françoise Paquet, et al.. La résonance Magnétique Nucléaire pour la chimie et la biologie. 29e colloque Biotechnocentre, Oct 2016, Seillac, France. ⟨hal-02920143⟩
Chapitre d'ouvrage1 document
- Gérard Lancelot, Françoise Paquet. NMR Studies of lac Operator and lac Repressor. Annual Reports on NMR Spectroscopy, pp.169-211, 2003. ⟨hal-02121524⟩