email : jean-baptiste.madinier[remplacer_par_at]cnrs-orleans.fr
Phone : +33 2.38.25.54.57
Engineer Mo2ving platform
- Métadonnées
Publications (Archives Hal)
Contact
isabelle.frapart@cnrs-orleans.fr 02.38.25.55.53
Disciplines
- Sciences du Vivant [q-bio]10
- Sciences du Vivant [q-bio]/Autre [q-bio.OT]8
- Chimie7
- Informatique [cs]3
- Sciences cognitives2
- Chimie/Chimie analytique1
- Sciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire1
- Sciences du Vivant [q-bio]/Immunologie/Immunothérapie1
- Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Dermatologie1
- Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC]1
Mots-clefs
Agonist AllD peptide Analog Antifungal defensin Antimicrobial peptide Botrytis cinerea Cathepsin Chemical protein synthesis enzymes linkers native chemical ligation solid-phase synthesis Defensin Disulfide-rich peptide Elastase Fluorescence microscopy Glucosylceramide Kiss1r Kisspeptin Kisspeptine Live bacteria Ovulation Puberte Puberty
- Kiss1r2
- Kisspeptine2
- Ovulation2
- Puberte2
- Puberty2
- Agonist1
- AllD peptide1
- Analog1
- Antifungal defensin1
- Antimicrobial peptide1
- Botrytis cinerea1
- Cathepsin1
- Chemical protein synthesis enzymes linkers native chemical ligation solid-phase synthesis1
- Defensin1
- Disulfide-rich peptide1
- Elastase1
- Fluorescence microscopy1
- Glucosylceramide1
- Kisspeptin1
- Live bacteria1
- Mammals1
- Mammifère1
- Molecular affinity1
- Near-infrared fluorescence NIRF1
- Neuropeptide1
- Neutrophil serine protease NSP1
- Novosphingobium capsulatum1
- Proteinase 31
- Reproduction1
Auteurs
Madinier Jean-Baptiste16 Aucagne Vincent14 Beltramo Massimiliano14 Lomet Didier11 Caraty Alain10 Delmas A.F.9 Galibert Mathieu8 Aucagne V.8 Robert Vincent8 Delmas Agnès7 Dardente Hugues7 Galibert M.6 Madinier J.-B.6 Decourt Caroline5 Marceau P.5 Marceau Philippe5 Landon Céline5 Anger Karine4 Robert V.4 Lomet D.4 Caraty A.3 Decourt C.3 Vishwanatha T.M.3 Madinier J.B3 Brigaud T.2 Chaume G.2 Kharrat Ons2 Nys Yves Y.2 Rahioui I.2 Robert Vincent2 Terrier V.P.2 Nehmé Reine2 Berges Magali2 Coste F.2 Meudal Hervé2 Castaing B.2 Madinier J.B.2 Delmas A.2 Delmas Agnès F.2 Bulet Philippe2 Réhault-Godbert Sophie2 Guyot Nicolas2 Labas Valérie2 Gautron Joël2 da Silva P.2 Chaloin Olivier2 Abboud Skander A1 Amoura Mehdi1 Anderson G.1 Anderson G.M.1 Anderson Greg M1 Anger K.1 Aumer Thomas1 Beltramo M.1 Briand Jean-Paul1 Cumin M.1 Decourt C C.1 Despres P.1 Herbison A.1 Herbison Allan E.1 Hoste A.1 Ilango Guy1 Knobloch Thomas1 Liu Xinhuai1 Mueller C.G.1 Mustafi Mainak1 Nasreddine Rouba1 Page Nicolas1 Piller Véronique1 Renoux Brigitte1 Schall Nicolas1 Seren Seda1 Wang Fengjuan1 Wartenberg Mylène1 Weisshaar James C.1 Yamaryo-Botté Yoshiki1 Muller Sylviane1 Papot Sébastien1 Thevissen Karin1 Zhu Yanyu1 Kuhn Lauriane1 Hammann Philippe1 Cammue Bruno1 Paquet Françoise1 Lecaille Fabien1 Lalmanach Gilles1 Mueller Christopher G1 Flacher V.1 Flacher Vincent1 Botté Cyrille1 Warschawski Dror1 Herve Virginie1 Hervé Virginie1 Vincent R.1 Saidi Ahlame1 Liu X.1 Chaloin O.1 Münz Christian1 Bonam Srinivasa Reddy1 Cumin Marie1
Revues
- Journal of Investigative Dermatology2
- Scientific Reports2
- Angewandte Chemie International Edition1
- Bioconjugate Chemistry1
- Journal of Medicinal Chemistry1
- Journal of Biological Chemistry1
- Proceedings of the National Academy of Sciences of the United States of America1
- International Journal of Molecular Sciences1
Institutions
- Université de Tours24
- Institut National de la Santé et de la Recherche Médicale24
- Université d'Orléans23
- Institut de Chimie - CNRS Chimie23
- Institut National de la Recherche Agronomique18
- Institut Français du Cheval et de l'Equitation [Saumur]17
- Université de Strasbourg5
- BioPark Archamps2
- Institut National des Sciences Appliquées de Lyon2
- Centre Hospitalier Universitaire [CHU Grenoble]2
- Commissariat à l'énergie atomique et aux énergies alternatives2
- Etablissement français du sang - Auvergne-Rhône-Alpes2
- Université de Rennes1
- Universität Zürich [Zürich] = University of Zurich1
- Université de Genève = University of Geneva1
- Centre Hospitalier Régional Universitaire de Tours1
- Aix Marseille Université1
- Institut Pasteur [Paris]1
- Université de La Réunion1
- Catholic University of Leuven = Katholieke Universiteit Leuven1
- IRD1
- University of Otago [Dunedin, Nouvelle-Zélande]1
- University of Wisconsin-Madison1
- Institute of Experimental Immunology [Zurich]1
- Structure Fédérative de Recherche en Biologie et Santé de Rennes1
- Hôpital Robert Debré1
- Université de Poitiers = University of Poitiers1
- Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement1
- École normale supérieure - Paris1
Laboratoires
- Centre de biophysique moléculaire23
- Physiologie de la reproduction et des comportements [Nouzilly]16
- Institute for Advanced Biosciences | Institut pour l'Avancée des Biosciences (Grenoble)2
- Unité de Recherches Avicoles2
- Institut de Chimie Organique et Analytique2
- Recherches Cunicoles2
- Centre de recherche du médicament Medalis - Drug Discovery Center [LabEx]2
- Biologie Fonctionnelle, Insectes et Interactions2
- Institut de Chimie de Strasbourg2
- Physiologie de la reproduction et des comportements [Nouzilly]1
- Chimie Physique et Chimie du Vivant1
- Institut de chimie des milieux et matériaux de Poitiers [UMR 7285]1
- Institut de Génétique et Développement de Rennes1
- Centre Interdisciplinaire de Nanoscience de Marseille1
- Immunopathologie et chimie thérapeutique1
- Processus Infectieux en Milieu Insulaire Tropical1
- Viral Immunobiology1
- Centre d’Etude des Pathologies Respiratoires [Tours]1
- Interactions Moléculaires Flavivirus-Hôtes1
Départements
Équipes de recherche
27 documents
Article dans une revue10 document
- Ons Kharrat, Françoise Paquet, Rouba Nasreddine, Jean-Baptiste Madinier, Reine Nehmé, et al.. Molecular recognition of fungal methylated glucosylceramides by ETD151 defensin. Journal of Biological Chemistry, 2025, 301 (9), pp.110587. ⟨10.1016/j.jbc.2025.110587⟩. ⟨hal-05250295⟩
- Ons Kharrat, Yoshiki Yamaryo-Botté, Rouba Nasreddine, Sébastien Voisin, Thomas Aumer, et al.. The antimicrobial activity of ETD151 defensin is dictated by the presence of glycosphingolipids in the targeted organisms. Proceedings of the National Academy of Sciences of the United States of America, 2025, 122 (7), pp.e2415524122. ⟨10.1073/pnas.2415524122⟩. ⟨hal-05304638⟩
- Céline Landon, Yanyu Zhu, Mainak Mustafi, Jean-Baptiste Madinier, Dominique Lelièvre, et al.. Real-Time Fluorescence Microscopy on Living E. coli Sheds New Light on the Antibacterial Effects of the King Penguin beta-Defensin AvBD103b. International Journal of Molecular Sciences, 2022, This article belongs to the Special Issue Antimicrobial Peptides: Structure and Mechanism of Biological Activity, 23 (2057), pp.2057. ⟨10.3390/ijms23042057⟩. ⟨hal-03860107⟩
- Ahlame Saidi, Mylène Wartenberg, J.B Madinier, Guy Ilango, Seda Seren, et al.. Monitoring Human Neutrophil Activation by a Proteinase 3 Near-Infrared Fluorescence Substrate-Based Probe. Bioconjugate Chemistry, 2021, 32 (8), pp.1782-1790. ⟨10.1021/acs.bioconjchem.1c00267⟩. ⟨hal-03525228⟩
- Adrien Brulefert, Melanie Kraemer, Marie Cumin, Amandine Selle, Astrid Hoste, et al.. Chikungunya virus envelope protein E2 provides a vector for targeted antigen delivery to human dermal CD14 + dendritic cells. Journal of Investigative Dermatology, 2021, ⟨10.1016/j.jid.2021.04.027⟩. ⟨hal-03259616⟩
- Skander A Abboud, Mehdi Amoura, J.B Madinier, Brigitte Renoux, Sébastien Papot, et al.. Enzyme‐Cleavable Linkers for Protein Chemical Synthesis through Solid‐Phase Ligations. Angewandte Chemie International Edition, 2021, 60 (34), pp.18612-18618. ⟨10.1002/anie.202103768⟩. ⟨hal-03335485⟩
- Fengjuan Wang, Srinivasa Reddy Bonam, Nicolas Schall, Lauriane Kuhn, Philippe Hammann, et al.. Blocking nuclear export of HSPA8 after heat shock stress severely alters cell survival. Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-34887-6⟩. ⟨hal-02137036⟩
- Caroline Decourt, Vincent Robert, Karine Anger, Mathieu Galibert, Jean-Baptiste Madinier, et al.. A synthetic kisspeptin analog that triggers ovulation and advances puberty. Scientific Reports, 2016, 6 (1), pp.26908. ⟨10.1038/srep26908⟩. ⟨hal-01406943⟩
- M. Cumin, A. Hoste, O. Chaloin, J.B Madinier, P. Despres, et al.. 403 Specific targeting of cutaneous antigen-presenting cells by Chikungunya virus envelope protein E2. Journal of Investigative Dermatology, 2016, 136 (9), pp.S229. ⟨10.1016/j.jid.2016.06.423⟩. ⟨hal-02137045⟩
- Massimiliano Beltramo, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, Philippe Marceau, et al.. Rational Design of Triazololipopeptides Analogs of Kisspeptin Inducing a Long-Lasting Increase of Gonadotropins. Journal of Medicinal Chemistry, 2015, 58 (8), pp.3459-3470. ⟨10.1021/jm5019675⟩. ⟨hal-01170460⟩
Communication dans un congrès5 document
- T.M. Vishwanatha, C. Decourt, V.P. Terrier, V. Robert, M. Galibert, et al.. Rational design of kisspeptin analogs for the control of reproduction. 4th Belgian Peptide Group Meeting, Feb 2018, Bruxelles, Belgium. ⟨hal-02892809⟩
- Nicolas Guyot, Virginie Hervé, Hervé Meudal, Jean-Baptiste Madinier, Valérie Labas, et al.. Insights into the structure-function relationship of egg defensins. XIVth European Poultry Conference, World's Poultry Science Association (WPSA). INT., Jun 2014, Stavanger, Norway. ⟨hal-02743609⟩
- Nicolas Guyot, Virginie Herve, Hervé Meudal, Jean-Baptiste Madinier, Valérie Labas, et al.. Functional and structural characterization of egg defensins. Banff Egg Forum, Jun 2014, Wroclaw, Poland. 12 diapositives. ⟨hal-02797356⟩
- Massimiliano Beltramo, Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, et al.. New KISS1R agonists with potential for the treatment of reproductive disorder. 11. International Symposium on GnRH: The hypothalamic-pituitary-gonadal axis in cancer and reproduction, Kenes International. USA., Feb 2014, Salzburg, Austria. ⟨hal-02742248⟩
- Massimiliano Beltramo, Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, et al.. Design and profiling of new selective KISS1R agonists that stimulate the reproductive system. 8. International Congress of Neuroendocrinology, Society for Behavioral Neuroendocrinology (SBN). USA., Aug 2014, Sydney, Australia. ⟨hal-02738894⟩
Poster12 document
- F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 21e congrès du Groupe Français des Peptides et des Protéines (GFPP), May 2019, Amboise, France. ⟨hal-02893471⟩
- T.M. Vishwanatha, C. Decourt C, V. Robert, M. Galibert, J.-B. Madinier, et al.. Long-lasting increase of gonadotropins by rational design of lipophilic kisspeptin analogs. 2018 International Symposium on Chemical Biology, Jan 2018, Genève, Switzerland. ⟨hal-02894282⟩
- F. Coste, G. Chaume, J.-B. Madinier, I. Rahioui, B. Castaing, et al.. Incorporation of trifluoromethylated pseudoproline in an entomotoxic knottin: effects on oxidative folding, 3D structure and biological activity. 35th European Peptide Symposium (EPS35), Aug 2018, Dublin, Ireland. ⟨hal-02894161⟩
- T.M. Vishwanatha, C. Decourt, V.P. Terrier, V. Robert, J.-B. Madinier, et al.. Rational design of kisspeptin analogs for the control of the reproductive system. 25th SCT Young Research Fellows meeting, Mar 2018, Orléans, France. ⟨hal-02894277⟩
- Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, M. Galibert, et al.. Induction of fertile ovulation and puberty advancement by a new kisspeptin analog. 18th International Congress on Animal Reproduction (ICAR), Jun 2016, Tours, France. 676 p., 2016, 18th International Congress on Animal Reproduction (ICAR). ⟨hal-01604087⟩
- M. Beltramo, V. Robert, D. Lomet, K. Anger, M. Galibert, et al.. A new selective kisspeptin analog, C6, that advance puberty in mice and stimulate fertile ovulation in ewe. British Society for Neuroendocrinology Annual Meeting, Sep 2016, Glasgow, United Kingdom. ⟨hal-02453336⟩
- Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, P. Marceau, et al.. Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotrophins. 19. Congrès du Groupe Français des Peptides et des Protéines, May 2015, Port-Bail, United States. 2015. ⟨hal-02793091⟩
- Caroline Decourt, Vincent Robert, Didier Lomet, Karine Anger, Mathieu Galibert, et al.. Induction of synchronized fertile ovulation by a new selective agonist of kisspeptin receptor. 1 Journées du GdR 3606 Repro, Apr 2015, Rennes, France. 105 p., 2015, 1ères Journées Scientifiques du GdR Repro. ⟨hal-02742326⟩
- Vincent Aucagne, Vincent Robert, Mathieu Galibert, Jean-Baptiste Madinier, P. Marceau, et al.. Rational design of triazolo-lipopeptides analogs of kisspeptin inducing a long-lasting increase of gonadotropins. 24. Meeting of the American Peptide Society, Jun 2015, Orlando, United States. 2015, 24th Meeting of the American Peptide Society. ⟨hal-02741835⟩
- Caroline Decourt, Karine Anger, Vincent Robert, Vincent Aucagne, Mathieu Galibert, et al.. Development of new kisspeptin analogs to stimulate the reproductive system. International Conference on Gonadotropins & Receptors, Sep 2014, Tours, France. , 2014, ICGRIII International Conference on Gonadotropins & Receptors. ⟨hal-02744014⟩
- Massimiliano Beltramo, V. Aucagne, R. Vincent, M. Galibert, J.B. Madinier, et al.. La kisspeptine : une nouvelle voie pour maitriser l’ovulation chez les petits ruminants ?. 5. Journées d'Animation Scientifique du département Phase (JAS Phase 2013), Oct 2013, Paris, France. 2013. ⟨hal-02805330⟩
- Massimiliano Beltramo, V. Aucagne, Vincent Robert, M. Galibert, J.B. Madinier, et al.. Design and functional profiling of new KISS1R agonists. 2. Annual Meeting of the GDR RCPG-PhysioMed, Oct 2013, Illkirch, France. 2013, 2nd Annual Meeting of the GDR RCPG-PhysioMed. ⟨hal-02745908⟩